KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
27.58
Human Site:
T175
Identified Species:
46.67
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
T175
K
D
R
K
L
H
G
T
A
Q
Q
L
L
Q
D
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
T175
K
D
R
K
L
H
G
T
A
Q
Q
L
L
Q
D
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
A245
E
N
M
T
H
T
C
A
S
G
T
P
K
E
R
Dog
Lupus familis
XP_547295
1021
115999
T213
K
D
R
K
L
H
G
T
A
Q
Q
L
L
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
T175
K
D
R
K
L
H
G
T
A
Q
Q
L
L
Q
D
Rat
Rattus norvegicus
O08874
985
112050
T176
K
D
R
K
L
H
G
T
A
Q
Q
L
L
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
Y231
A
E
N
M
I
Q
M
Y
A
N
G
T
P
K
E
Chicken
Gallus gallus
XP_422357
1013
114806
T202
K
D
R
K
L
L
A
T
A
Q
Q
M
L
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
T163
K
D
R
K
L
L
A
T
A
Q
Q
M
L
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
V60
L
T
P
I
E
F
R
V
E
E
V
R
H
H
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
F229
D
H
I
Q
S
P
M
F
A
R
K
P
E
S
Y
Red Bread Mold
Neurospora crassa
P87253
1142
127954
A200
K
K
S
K
L
D
A
A
A
K
R
V
E
S
K
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
6.6
80
N.A.
80
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
33.3
86.6
N.A.
86.6
N.A.
0
N.A.
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
22
15
72
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
50
0
0
0
8
0
0
0
0
0
0
0
0
50
% D
% Glu:
8
8
0
0
8
0
0
0
8
8
0
0
15
8
8
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
36
0
0
8
8
0
0
0
0
% G
% His:
0
8
0
0
8
36
0
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
58
8
0
58
0
0
0
0
0
8
8
0
8
8
8
% K
% Leu:
8
0
0
0
58
15
0
0
0
0
0
36
50
0
0
% L
% Met:
0
0
8
8
0
0
15
0
0
0
0
15
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
8
0
0
0
0
0
15
8
0
0
% P
% Gln:
0
0
0
8
0
8
0
0
0
50
50
0
0
50
0
% Q
% Arg:
0
0
50
0
0
0
8
0
0
8
8
8
0
0
8
% R
% Ser:
0
0
8
0
8
0
0
0
8
0
0
0
0
15
0
% S
% Thr:
0
8
0
8
0
8
0
50
0
0
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _